Abstract Detail



Poster Session

Wintola, Olubunmi Abosede [1], Afolayan, Anthony Jide [2].

Phytochemical evaluation, antioxidant and antimicrobial activities of the root extracts of Hydnora africana Thunb. used for the management of dysentery in Eastern Cape Province.

 In this study, the phytochemical content, antioxidant and antibacterial activities of the root extracts of Hydnora africana were evaluated. The presence of phytochemicals and antioxidant activity was assessed using standard methods. The agar well diffusion method was used to determine the susceptibility of bacterial strains on the root extracts of Hydnora africana. The minimum inhibitory concentration was determined by the microdilution test. Phytochemical assays revealed the presence of equivalent quantity of alkaloids, tannins, flavonoids, saponins and phenols in the extracts. Antioxidant activity showed lower ferric reducing activities, moderate nitric oxide, moderate DPPH and higher ABTS scavenging activities of the plant when compared with BHT and gallic acid. The antimicrobial activity of H. africana against all the tested organisms demonstrated a mean zone diameter of inhibition ranging from 0 to 25 mm. The MIC of the extracts ranged from 0.071 to 5.0 mg/mL. The antimicrobial activity of extracts was compared with the standard antibiotics (Ciprofloxacin 0.0125 mg/ml). The water and methanol extracts were also shown as the best solvents of extraction for the phytochemicals. The methanol and acetone extracts of H. africana exhibited a significant antibacterial and antioxidant activities, suggesting the presence of either good bioactive potency or the high concentration of the active principle in the extracts. This may serve as a guide for selecting bio-medicinal substances of plant origin for the management of dysentery.


1 - University of Fort Hare, Alice, Botany, P Bag 1314X, 1 King William's Road Alice, Alice, Eastern Cape, 5700, South Africa
2 - University of Fort Hare, Alice, Botany, P Bag 1314X, 1 King William's Road Alice, Eastern Cape, 5700, South Africa

Keywords:
antibacterial
Hydnora africna
antioxidant
South Africa.

Presentation Type: Poster
Number:
Abstract ID:80
Candidate for Awards:None